thrombin inhibitor meaning in English
凝血酶抑制体
凝血抑制因子
Examples
- Thrombin inhibitor ; expression in methylotrophic yeast pichia pastoris ; anticoagulant
山蛭素凝血酶抑制剂毕赤酵母表达抗凝剂 - Based on the structure and function analysis of hirudin , a potent thrombin inhibitor , and some platelet aggregation inhibitors , which contain the recognition sequence argglyasp as their functional motif , two chimeric antithrombotic molecules were designed by introducing rgd sequence to hirudin cterminus . these chimera genes were constructed by pcr and inserted into the expression vector pet21a , the constructs were confirmed by restriction enzyme digestion and dna sequence analysis . these recombinant plasmids were transformed into
经限制酶消化和dna序列分析,证明两种重组质粒与设计完全一致。由于rgd -水蛭素嵌合基因上游连接了金黄色葡萄球菌蛋白a spa的信号肽序列,在iptg诱导下两种嵌合分子都获得了分泌表达,表达产物主要集中在细胞周质空间。